SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameNOC4
Systematic nameYPR144C
AliasUTP19
DescriptionNucleolar complex protein 4

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionQ06512
SGD YPR144C
Gene Ontology (GO)
Cellular componentGO:0030692Noc4p-Nop14p complexIPI:SGD.
Cellular componentGO:0005732small nucleolar ribonucleoprotein complexIPI:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Molecular functionGO:0030515snoRNA bindingIDA:HGNC.
Biological processGO:000636535S primary transcript processingIMP:HGNC.
Biological processGO:0042274ribosomal small subunit biogenesis and asse...IMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length552
Molecular weight63637

	---------+----------+----------+----------+----------+
MVLLISEIKD IAKRLTAAGD RKQYNSIIKL INELVIPENV TQLEEDETEK   50
NLRFLVMSLF QIFRKLFSRG DLTLPSSKKS TLEKEQFVNW CRKVYEAFKT   100
KLLAIISDIP FETSLGLDSL DVYLQLAELE STHFASEKGA PFFPNKTFRK   150
LIIALWSSNM GEIEDVKSSG ASENLIIVEF TEKYYTKFAD IQYYFQSEFN   200
QLLEDPAYQD LLLKNVGKWL ALVNHDKHCS SVDADLEIFV PNPPQAIENE   250
SKFKSNFEKN WLSLLNGQLS LQQYKSILLI LHKRIIPHFH TPTKLMDFLT   300
DSYNLQSSNK NAGVVPILAL NGLFELMKRF NLEYPNFYMK LYQIINPDLM   350
HVKYRARFFR LMDVFLSSTH LSAHLVASFI KKLARLTLES PPSAIVTVIP   400
FIYNLIRKHP NCMIMLHNPA FISNPFQTPD QVANLKTLKE NYVDPFDVHE   450
SDPELTHALD SSLWELASLM EHYHPNVATL AKIFAQPFKK LSYNMEDFLD   500
WNYDSLLNAE SSRKLKTLPT LEFEAFTNVF DNEDGDSEAS SQGNVYLPGV   550
AW                                                       552