SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameMSH3
Systematic nameYCR092C
DescriptionDNA mismatch repair protein MSH3

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionP25336
SGD YCR092C
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
Cellular componentGO:0005634nucleusIDA:SGD.
Molecular functionGO:0032135DNA insertion or deletion bindingIDA:SGD.
Molecular functionGO:0000406double-strand/single-strand DNA junction bi...IDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0000710meiotic mismatch repairIMP:SGD.
Biological processGO:0000735removal of nonhomologous endsIGI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length1047
Molecular weight119754

	---------+----------+----------+----------+----------+
MVIGNEPKLV LLRAKSSANR FILLNLLTIM AGQPTISRFF KKAVKSELTH   50
KQEQEVAVGN GAGSESICLD TDEEDNLSSV ASTTVTNDSF PLKGSVSSKN   100
SKNSEKTSGT STTFNDIDFA KKLDRIMKRR SDENVEAEDD EEEGEEDFVK   150
KKARKSPTAK LTPLDKQVKD LKMHHRDKVL VIRVGYKYKC FAEDAVTVSR   200
ILHIKLVPGK LTIDESNPQD CNHRQFAYCS FPDVRLNVHL ERLVHHNLKV   250
AVVEQAETSA IKKHDPGASK SSVFERKISN VFTKATFGVN STFVLRGKRI   300
LGDTNSIWAL SRDVHQGKVA KYSLISVNLN NGEVVYDEFE EPNLADEKLQ   350
IRIKYLQPIE VLVNTDDLPL HVAKFFKDIS CPLIHKQEYD LEDHVVQAIK   400
VMNEKIQLSP SLIRLVSKLY SHMVEYNNEQ VMLIPSIYSP FASKIHMLLD   450
PNSLQSLDIF THDGGKGSLF WLLDHTRTSF GLRMLREWIL KPLVDVHQIE   500
ERLDAIECIT SEINNSIFFE SLNQMLNHTP DLLRTLNRIM YGTTSRKEVY   550
FYLKQITSFV DHFKMHQSYL SEHFKSSDGR IGKQSPLLFR LFSELNELLS   600
TTQLPHFLTM INVSAVMEKN SDKQVMDFFN LNNYDCSEGI IKIQRESESV   650
RSQLKEELAE IRKYLKRPYL NFRDEVDYLI EVKNSQIKDL PDDWIKVNNT   700
KMVSRFTTPR TQKLTQKLEY YKDLLIRESE LQYKEFLNKI TAEYTELRKI   750
TLNLAQYDCI LSLAATSCNV NYVRPTFVNG QQAIIAKNAR NPIIESLDVH   800
YVPNDIMMSP ENGKINIITG PNMGGKSSYI RQVALLTIMA QIGSFVPAEE   850
IRLSIFENVL TRIGAHDDII NGDSTFKVEM LDILHILKNC NKRSLLLLDE   900
VGRGTGTHDG IAISYALIKY FSELSDCPLI LFTTHFPMLG EIKSPLIRNY   950
HMDYVEEQKT GEDWMSVIFL YKLKKGLTYN SYGMNVAKLA RLDKDIINRA   1000
FSISEELRKE SINEDALKLF SSLKRILKSD NITATDKLAK LLSLDIH      1047