SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameLSM4
Systematic nameYER112W
AliasSDB23, USS1
DescriptionU6 snRNA-associated Sm-like protein LSm4

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionP40070
SGD YER112W
Gene Ontology (GO)
Cellular componentGO:0005732small nucleolar ribonucleoprotein complexIPI:SGD.
Cellular componentGO:0005688snRNP U6IDA:SGD.
Cellular componentGO:0046540U4/U6 x U5 tri-snRNP complexIDA:SGD.
Molecular functionGO:0003723RNA bindingTAS:SGD.
Biological processGO:0006402mRNA catabolic processTAS:SGD.
Biological processGO:0000398nuclear mRNA splicing, via spliceosomeIPI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length187
Molecular weight21276

	---------+----------+----------+----------+----------+
MLPLYLLTNA KGQQMQIELK NGEIIQGILT NVDNWMNLTL SNVTEYSEES   50
AINSEDNAES SKAVKLNEIY IRGTFIKFIK LQDNIIDKVK QQINSNNNSN   100
SNGPGHKRYY NNRDSNNNRG NYNRRNNNNG NSNRRPYSQN RQYNNSNSSN   150
INNSINSINS NNQNMNNGLG GSVQHHFNSS SPQKVEF                 187