SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameKCC4
Systematic nameYCL024W
DescriptionProbable serine/threonine-protein kinase KCC4

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI       
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets."
Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.
Mol Cell Proteomics. 4(6):741-51 (2005) [15699485]

Cross References
Swiss-Prot accessionP25389
SGD YCL024W
Gene Ontology (GO)
Cellular componentGO:0005935cellular bud neckIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0007120axial cellular bud site selectionTAS:SGD.
Biological processGO:0007117budding cell bud growthIGI:SGD.
Biological processGO:0000135septin checkpointIGI:SGD.
Biological processGO:0000921septin ring assemblyIGI:SGD.
EC number 2.7.11.1

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
675Phosphoserine.
848Phosphoserine.

Sequence Information
Sequence length1037
Molecular weight116475

	---------+----------+----------+----------+----------+
MTVANTETHS AAKPSSTIGP WKLGETLGFG STGKVQLAQH ERTGHRTAVK   50
VISKSIFNNN GNHSNDDSVL PYNIEREIVI MKLLSHPNVL SLYDVWETNN   100
NLYLILEYAE KGELFNLLVD HGPLPEREAI NCFRQIIIGI SYCHALGIVH   150
RDLKPENLLL DSFYNIKIAD FGMAALQTDA DLLETSCGSP HYAAPEIVSG   200
LPYEGFASDV WSCGVILFAL LTGRLPFDEE NGNVRDLLLK VQKGQFEMPN   250
DTEISRDAQD LIGKILVVDP RQRIKIRDIL SHPLLKKYQT IKDSKSIKDL   300
PRENTYLYPL ADSNNHTSAS IDDSILQNLV VLWHGRHADD IVSKLKENGT   350
NKEKILYALL YRFKLDSVRG SNKKNRNKIK KTKKNKRSST LSSSSSLLLN   400
NRSIQSTPRR RTSKRHSREF SSSRKRSSFL LSSNPTDSSP IPLRSSKRIT   450
HINVASANTQ ATPSGVPNPH KRNSKKRSSK RLSYMPNTKR SSLTSKSLSN   500
FTNLIDDDDW EYIEKDAKRT SSNFATLIDE IFEPEKFELA KREKAELQRK   550
VQEAKRQSVN AQKINEDEFG SEVSDGMKEL KKINDKVSSP LINYEFSQQE   600
LLQDIDTLLT NRYQLSSYTR PISRLDPGLT PVTETLPNNL KEKTALLQDT   650
EKKIIETIRR SKFLGSLLNV RGGLSPGKSE LAPIEESPIV STTPLIYNDR   700
MEPRRISDVE VPHFTRKSKH FTTANNRRSV LSLYAKDSIK DLNEFLIKED   750
PDLPPQGSTD NESRSEDPEI AESITDSRNI QYDEDDSKDG DNVNNDNILS   800
DFPQGVGISQ EYDMKDKNPN QSPISKSAEP TLVVKLPSLS SFQGKNASGL   850
GLYQREPSKV TLPSLTSNNS SVGENIEDGA EKGTESEKIA ASLSDDDLKE   900
DNDKKDNDTV NAPTTVKKPP NSVLLKKFSK GKILELEIHA KIPEKRLYEG   950
LHKLLEGWKQ YGLKNLVFNI TNMIITGKLV NDSILFLRST LFEIMVLPNG   1000
DGRSLIKFNK KTGSTKTLTK LATEIQIILQ KEGVLDK                 1037