SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameJIP4
Systematic nameYDR475C/YDR474C
DescriptionUncharacterized protein JIP4

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ03361
SGD YDR475C/YDR474C
Gene Ontology (GO)
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
552Phosphoserine.

Sequence Information
Sequence length876
Molecular weight98691

	---------+----------+----------+----------+----------+
MVVRDQDEAL RNSYKYVKLY VRQDQLEDTV DILAKQDEDK SNNDDRRSLA   50
SILDSSSSVK KKGKGSNEKY LPCVSFNTVP RSRVSSPLDE EKREFPGVQI   100
SADYTMEEYY DDESGFTSDN NADYFSGNSY SSRREGSASP GRYSSPPPAS   150
KRNIKIGKMF KISENGKIVR EDYPTTPTDI NDALVISRAY ANWRQLWIKK   200
KNQIDHRLEQ KRDFFNYPTI LFPPNKKKSS EGATPTIKFN PPIEDGFTPL   250
TKSQKRKERV LSEKVGFPNT PRTILCHISG RKHTWVALDW ALRTLIQNTD   300
HIVVLANLPR LTKNNFEDND SMSERKRMLM MMDDSRSVSS ARRSRSRSRS   350
RSICTRRALS LGPEESDNKL KHQNFIEWTS GYTQNEIERK LQDLFDYVTL   400
IIPQDRSVKV TVEILIGKTK KTLLEAINIY LPDFFVSSTL RWERTDSLVR   450
WKSNFLTDKL CTNFPIPTFI VPAKRMFDLE IDLQKEFKEP EVTKQKNTSG   500
PKPGFSHSKS ADASIPTISN IKRKQDNDYS IDSLCYAPEA NGANNSSREE   550
ASDDELNAFK DDENDVMSVK SLTSNISVKE KLCTMARKRR KSMAQQLNDA   600
DHDSSIPPGQ RHLKKLNIIL ESSLKFSLEI DSITDSIENG DVDEKRAHSM   650
ESGFEELKRV ITGGAPPRHV ATPQRSMLDV LDNPSSSRSK SKSRSSSKSR   700
IRDKSKPSSP TATDINSSAS ASRSRSPQIK FASSVKNVDG NAALGAIKSR   750
HSLDSPGDQQ QQHHHHHHRD TDQLSVPGLP HLAPSKSYSV SSGNKDSSLR   800
KVSSSSSLRK VKSNDSNSGK RIKKPVVTSA HLKPSSGGGG LFSFFKSKSR   850
SPSSFRKEDE SKNTPKRGGL FGFGRL                             876