SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameITT1
Systematic nameYML068W
DescriptionTranslation termination inhibitor protein ITT1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1K23        
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionQ04638
SGD YML068W
Gene Ontology (GO)
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0006449regulation of translational terminationIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length464
Molecular weight54096

	---------+----------+----------+----------+----------+
MALTQFENDL EILRDMYPEL EMKSVKVEEE GEFPQRINGK LLFKISLLAD   50
VNIEFGEQHM LLSNLSNECV EFTIYSCHYP DIRRCVVMDI KSLWISTDEK   100
KMLIDKALRL VEETVDMSIE FADSFTSILI LIFGFLIDDT AILLFPNGIR   150
KCLTQDQYDL FKQISEEATL QKVSRSNYHC CICMEMEKGV RMIKLPCENA   200
NVEHYLCRGC AKSYFTAMIQ ENRISSVRCP QCEYKELKLE DFKSYKKMLK   250
ALFTPLIPVS FLKEVIDTEL CERYEKMFYN QAATRLSKYC PYACVTCRRC   300
DSWCTKEDLD DAMIQCQKCH FVFCFDCLHA WHGYNNKCGK KVSLSTDIIE   350
EYLDDTVTSY ERKRKLEAKY GRRVLELEVN DYLAEKMLDL AIKKEGSNLQ   400
RCPKCKVVVE RSEGCNKMKC EVCGTLFCFI CGVLLYPEDP YEHFREAYSG   450
CYGRLFEGMP GTET                                          464

	* Ubiquitinated lysine is denoted as red color.