SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameIQG1
Systematic nameYPL242C
AliasCYK1
DescriptionRas GTPase-activating-like protein IQG1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI    RPN10 Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ12280
SGD YPL242C
Gene Ontology (GO)
Cellular componentGO:0000142cellular bud neck contractile ringIDA:SGD.
Molecular functionGO:0008092cytoskeletal protein bindingIPI:SGD.
Biological processGO:0007015actin filament organizationIPI:SGD.
Biological processGO:0000910cytokinesisIMP:SGD.
Biological processGO:0006970response to osmotic stressIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
354Phosphoserine.

Sequence Information
Sequence length1495
Molecular weight172830

	---------+----------+----------+----------+----------+
MTAYSGSPSK PGNNNSYLNR YVENLGTNVT PPLRPQSSSK INSSLNIASP   50
SHLKTKTSAS NSSATILSKK VESSVSKLKP SLPNKLVGKY TVDLSNYSKI   100
ELRYYEFLCR VSEVKIWIEA VIEEALPSEI ELCVGDSLRN GVFLAKLTQR   150
INPDLTTVIF PAGDKLQFKH TQNINAFFGL VEHVGVPDSF RFELQDLYNK   200
KNIPQVFETL HILISMINKK WPGKTPALTN VSGQISFTKE EIAACKKAWP   250
RIRDFKSLGT NINTAPASPE EPKEKRSGLI KDFNKFERPN IPVEEILITP   300
RKNITDANCS DFSNTPSPYN EAPKMSNLDV VVEKRKFTPI EPSLLGPTPS   350
LEYSPIKNKS LSYYSPTISK YLTYDTEFYT RRSRAREEDL NYYQTFKYSP   400
SHYSPMRRER MTEEQFLEKV VQLQNICRGV NTRFNLYIQK RLLNLFEQDI   450
LRFQACLRGN KFRVLSSMYL PIRRAKIDVP HVEAIQSRIK GSRIRYKYDK   500
LKFTLSRFSC TVELLQAYCR SKLLKTTVNT KLNDIEISHY PLTKLQSYMR   550
ASYVRKKVMS LNTKLNDERE SIMKFSAIIR GNVVRCSEDA ILSAVHDVHK   600
ENISKLQSLI RGIFTRSCLA SIIYSLGKEN CNIIQLSACI RGNAVRHKVQ   650
SLFAPENNLS ETVHDLQGLV RGILVRYTLD LVDDIVEYNN LALFQAFSRG   700
ALVRESLDQK SSFYKRNVRS VIMIQSWIRK SLQRSAYLEL LDCPNPSLWA   750
VKKFVHLLNG TATIEEVQNQ LESCQASLDS ENMKKERLLK SIRQQLNING   800
VLDKFGLLKD KDHELGISDS TIPKSKYQKY EKLFYMLQVD PSYWKLLYLK   850
EPEFVAKNVY MTFGTVNQRM NDRERSYFTR FVCEMLQNAI NEAPSIESFL   900
DNRSQFWQTI LQDFLRRESP EFFSIIVPVL DYLSDPVVDF ESDPYKIYQE   950
IHGFSSPQHC SPVDDASTKN KFIDNLRCLW HAIEMVAEIY TRKVHTIPVE   1000
IRYLCTKIFC YAADKNIEEI DSLRAISSIL VNVFVSEYLV NREYYGYKDS   1050
NVQKNNQKID ILMKSLATVF EIKNFDGFLD PLNQYANEIK PHIKDVLYNV   1100
LVDPEYEQEG DRLIYLDMVS PSPKLELLTE KVLEISGKFE EYLNEFPEAD   1150
ILHDILEKNL DNSSFPRSGR VTLELDASAY RFLVSDDKMR KIYDQVKRAF   1200
VYMMQIEDVD TNLYDLSIST ILPQDEPNFA NFLEQNPKIR DDPMIQKLKP   1250
LKYFTLKNVT LKKIHELEST GTFCSSDNKL QNFLNDIANT IKNPNYAIDY   1300
VTQEIYITKE TLTKISEMNH SLDIELSRLK KHVDHTIKDF QKAKDFSPVH   1350
KSKFGNFKNA VKKVQGRERS ELQGMKFKWN TKQLYERGVL KTIRGEKLAE   1400
LTVKVFGSSG PKFPDIIFKI STSDGSRFGI QMIDKRKGPD KRYSDDVDSF   1450
SFKDLIKTQV EPKIETWKLF HSNVVVNNSQ LLHLIVSFFY KRNAL        1495