SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameIMD2
Systematic nameYHR216W
AliasPUR5
DescriptionInosine-5'-monophosphate dehydrogenase IMD2

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (HB-ubiquitin (a tandem affinity tag under denaturing conditions)), LC/MS
Reference"A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking."
Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P.
Mol Cell Proteomics. 5(4):737-48 (2006) [16432255]

Cross References
Swiss-Prot accessionP38697
SGD YHR216W
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
Molecular functionGO:0003938IMP dehydrogenase activityTAS:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0006183GTP biosynthetic processTAS:SGD.
EC number 1.1.1.205

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length523
Molecular weight56530

	---------+----------+----------+----------+----------+
MAAIRDYKTA LDFTKSLPRP DGLSVQELMD SKIRGGLTYN DFLILPGLVD   50
FASSEVSLQT KLTRNITLNI PLVSSPMDTV TESEMATFMA LLGGIGFIHH   100
NCTPEDQADM VRRVKNYENG FINNPIVISP TTTVGEAKSM KEKYGFAGFP   150
VTTDGKRNAK LVGVITSRDI QFVEDNSLLV QDVMTKNPVT GAQGITLSEG   200
NEILKKIKKG RLLVVDEKGN LVSMLSRTDL MKNQNYPLAS KSANTKQLLC   250
GASIGTMDAD KERLRLLVKA GLDVVILDSS QGNSIFELNM LKWVKESFPG   300
LEVIAGNVVT REQAANLIAA GADGLRIGMG TGSICITQEV MACGRPQGTA   350
VYNVCEFANQ FGVPCMADGG VQNIGHITKA LALGSSTVMM GGMLAGTTES   400
PGEYFYQDGK RLKAYRGMGS IDAMQKTGTK GNASTSRYFS ESDSVLVAQG   450
VSGAVVDKGS IKKFIPYLYN GLQHSCQDIG CRSLTLLKNN VQRGKVRFEF   500
RTASAQLEGG VHNLHSYEKR LHN                                523