SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameHXT4
Systematic nameYHR092C
AliasLGT1, RAG1
DescriptionLow-affinity glucose transporter HXT4

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1K45        
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS
Reference"A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery."
Hitchcock AL, Auld K, Gygi SP, Silver PA.
Proc Natl Acad Sci U S A. 100(22):12735-40 (2003) [14557538]

Cross References
Swiss-Prot accessionP32467
SGD YHR092C
Gene Ontology (GO)
Molecular functionGO:0005353fructose transporter activityTAS:SGD.
Molecular functionGO:0005355glucose transporter activityIDA:SGD.
Molecular functionGO:0015578mannose transporter activityTAS:SGD.
Molecular functionGO:0015146pentose transporter activityIMP:SGD.
Biological processGO:0008645hexose transportTAS:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length576
Molecular weight63910

	---------+----------+----------+----------+----------+
MSEEAAYQED TAVQNTPADA LSPVESDSNS ALSTPSNKAE RDDMKDFDEN   50
HEESNNYVEI PKKPASAYVT VSICCLMVAF GGFVFGWDTG TISGFVAQTD   100
FIRRFGMKHH DGTYYLSKVR TGLIVSIFNI GCAIGGIILA KLGDMYGRKM   150
GLIVVVVIYI IGIIIQIASI NKWYQYFIGR IISGLGVGGI AVLSPMLISE   200
VSPKHIRGTL VSCYQLMITL GIFLGYCTNY GTKTYTNSVQ WRVPLGLGFA   250
WALFMIGGMT FVPESPRYLV EVGKIEEAKR SIALSNKVSA DDPAVMAEVE   300
VVQATVEAEK LAGNASWGEI FSTKTKVFQR LIMGAMIQSL QQLTGDNYFF   350
YYGTTVFTAV GLEDSFETSI VLGIVNFAST FVGIFLVERY GRRRCLLWGA   400
ASMTACMVVF ASVGVTRLWP NGKKNGSSKG AGNCMIVFTC FYLFCFATTW   450
APIPFVVNSE TFPLRVKSKC MAIAQACNWI WGFLIGFFTP FISGAIDFYY   500
GYVFMGCLVF SYFYVFFFVP ETKGLTLEEV NTLWEEGVLP WKSPSWVPPN   550
KRGTDYNADD LMHDDQPFYK KMFGKK                             576

	* Ubiquitinated lysine is denoted as red color.