SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameHRQ1
Systematic nameYDR291W
DescriptionPutative ATP-dependent helicase HRQ1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ05549
SGD YDR291W
Gene Ontology (GO)
Cellular componentGO:0005634nucleusIDA:SGD.
EC number 3.6.1.-

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length1077
Molecular weight123550

	---------+----------+----------+----------+----------+
MEEGPIKKKL KSAGQGSGKT DAFRNFEQFF FRLNTLYTFL ICRKHVVPTF   50
KTLCGPIETA LKRTVTKEDL AMVMALMPRE CVFKYIDENQ IYTETKIFDF   100
NNGGFQQKEN DIFELKDVDD QNQTQKSTQL LIFEFIDGTM QRSWSASDRF   150
SQIKIPTYTT EEMKKMISKR EALFKSRLRE FILEKEKANL DPFSELTNLA   200
QKYIPRERDY EDPIEAMMKA KQESNEMSIP NYSNNSVITT IPQMIEKLKS   250
TEFYASQIKH CFTIPSRTAK YKGLCFELAP EVYQGMEHEN FYSHQADAIN   300
SLHQGENVII TTSTSSGKSL IYQLAAIDLL LKDPESTFMY IFPTKALAQD   350
QKRAFKVILS KIPELKNAVV DTYDGDTEPE ERAYIRKNAR VIFTNPDMIH   400
TSILPNHANW RHFLYHLKLV VVDELHIYKG LFGSHVALVM RRLLRLCHCF   450
YENSGLQFIS CSATLKSPVQ HMKDMFGINE VTLIHEDGSP TGAKHLVVWN   500
PPILPQHERK RENFIRESAK ILVQLILNNV RTIAFCYVRR VCELLMKEVR   550
NIFIETGRED LVTEVMSYRG GYSASDRRKI EREMFHGNLK AVISTNALEL   600
GIDIGGLDAV LMCGFPLSMA NFHQQSGRAG RRNNDSLTLV VASDSPVDQH   650
YVAHPESLLE VNNFESYQDL VLDFNNILIL EGHIQCAAFE LPINFERDKQ   700
YFTESHLRKI CVERLHHNQD GYHASNRFLP WPSKCVSLRG GEEDQFAVVD   750
ITNGRNIIIE EIEASRTSFT LYDGGIFIHQ GYPYLVKEFN PDERYAKVQR   800
VDVDWVTNQR DFTDVDPQEI ELIRSLRNSD VPVYFGKIKT TIIVFGFFKV   850
DKYKRIIDAI ETHNPPVIIN SKGLWIDMPK YALEICQKKQ LNVAGAIHGA   900
QHAIMGMLPR FIVAGVDEIQ TECKAPEKEF AERQTKRKRP ARLIFYDSKG   950
GKYGSGLCVK AFEHIDDIIE SSLRRIEECP CSDGCPDCVA ASFCKENSLV   1000
LSKPGAQVVL HCILGHSEDS FIDLIKDGPE PNMPEIKVET VIPVSEHVNF   1050
SDDFKIIDVR RATKDDTHTN EIIKKEI                            1077