SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameHMX1
Systematic nameYLR205C
DescriptionHeme-binding protein HMX1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (HB-ubiquitin (a tandem affinity tag under denaturing conditions)), LC/MS
Reference"A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking."
Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P.
Mol Cell Proteomics. 5(4):737-48 (2006) [16432255]

Cross References
Swiss-Prot accessionP32339
SGD YLR205C
Gene Ontology (GO)
Cellular componentGO:0005783endoplasmic reticulumIDA:SGD.
Cellular componentGO:0016021integral to membraneNAS:UniProtKB.
Molecular functionGO:0020037heme bindingNAS:UniProtKB.
Molecular functionGO:0004392heme oxygenase (decyclizing) activityIEP:SGD.
Molecular functionGO:0004601peroxidase activityIDA:SGD.
Biological processGO:0042167heme catabolic processIGI:SGD.
Biological processGO:0006879iron ion homeostasisIEP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length317
Molecular weight37179

	---------+----------+----------+----------+----------+
MEDSSNTIIP SPTDVGALAN RINFQTRDAH NKINTFMGIK MAIAMRHGFI   50
YRQGILAYYY VFDAIEQEID RLLNDPVTEE ELQTSTILKQ FWLEDFRRST   100
QIYKDLKLLY SNTFKSTESL NEFLATFQKP PLLQQFINNI HENIHKEPCT   150
ILSYCHVLYL ALFAGGKLIR SNLYRRLGLF PNFEKLSQKE LVKKGTNFFT   200
FSDLGPTEET RLKWEYKKNY ELATRTELTE AQKLQIISVA EGIFDWNFNI   250
VAEIGELNRR ELMGKFSFKC ITYLYEEWMF NKDSATRRAL HTVMLLVLSI   300
IAIWVLYFLV KSFLSIV                                       317