SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameGRX3
Systematic nameYDR098C
DescriptionMonothiol glutaredoxin-3

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionQ03835
SGD YDR098C
Gene Ontology (GO)
Cellular componentGO:0005634nucleusIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Molecular functionGO:0030508thiol-disulfide exchange intermediate activityIGI:SGD.
Biological processGO:0006879iron ion homeostasisIGI:SGD.
Biological processGO:0006979response to oxidative stressIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length285
Molecular weight32481

	---------+----------+----------+----------+----------+
MCSFQVPSAF SFNYTSYCYK RHQARYYTAA KLFQEMPVIE INDQEQFTYL   50
TTTAAGDKLI VLYFHTSWAE PCKALKQVFE AISNEPSNSN VSFLSIDADE   100
NSEISELFEI SAVPYFIIIH KGTILKELSG ADPKEYVSLL EDCKNSVNSG   150
SSQTHTMENA NVNEGSHNDE DDDDEEEEEE TEEQINARLT KLVNAAPVML   200
FMKGSPSEPK CGFSRQLVGI LREHQVRFGF FDILRDESVR QNLKKFSEWP   250
TFPQLYINGE FQGGLDIIKE SLEEDPDFLQ HALQS                   285