SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameGIS4
Systematic nameYML006C
DescriptionProtein GIS4

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MONO RINGSCFGRR1   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
MethodWestern blot
Reference"SCFGrr1-mediated ubiquitination of Gis4 modulates glucose response in yeast."
La Rue J, Tokarz S, Lanker S.
J Mol Biol. 349(4):685-98 (2005) [15890364]

Cross References
Swiss-Prot accessionQ04233
SGD YML006C
Gene Ontology (GO)
Cellular componentGO:0005886plasma membraneIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0006873cell ion homeostasisIMP:SGD.
Biological processGO:0007242intracellular signaling cascadeIGI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
622Phosphoserine.
642Phosphoserine.
707Phosphoserine.
720Phosphoserine.

Sequence Information
Sequence length774
Molecular weight87140

	---------+----------+----------+----------+----------+
MQKSVRVGDY FDNDDNGLWS WYLTNLRLGD FEELIGNQLK YTLLKRFLNS   50
HFYGDNNISA RPNKKILLVS IPENVHEDIS ILEIFLKDYF HLEKLEHIQI   100
SKLTHSHCYN HENHYLLTDN LNNFQDPTFL EFASTSWQVQ KNSKALNNNN   150
RNSIPPPTIS SSKASNGKLE SNVSDDQWSN INTQTSTATR TNTNTRTLTS   200
PDTVDINVTS VNSQSNNNDT PQDNENEVDE EDATSSIVLN FSHSRTVDSK   250
PNRLPKIFPS YTNEDYTPSH SEIMSIDSFA GEDVSSTYPG QDLSLTTARR   300
EDESGQDEVE DHYSRVSHDL GDESIDQASY SMESSVSYTS YSSSSNSSSA   350
HYSLSSSSRG NPKRENIDHT NATYVSELSS ITSSIDNLTT STTPEEEDNL   400
IHHNYDAQGY GSGEDDGEEV YDDEDLSSSD YSVLSILPSI SICDSLGYFR   450
LVLQSILIQD PDTKEIFTAI RQSNNKPTMA SVTDDWLLYD SNFSMNNLQI   500
LTLQDLLDIK RSFPKILFYT MVIVTNSGKQ VEEEFKNPNY DNREGISKEQ   550
PLDSELSLTN DPQQYFPTAY NNGYNDYIDD EDDEDDGDDA SLSEQSGPQM   600
YIPTRMESNV TTAHRSIRTV NSIGEWAFNR HNSVTKIDKS NSNELDNSKT   650
GESTVLSSEP HPMTQLSNSN TTSSNFSHSL KTKNSHKPNS KGNNESNSKN   700
ELKKIKSSIN AMSAVERSKS LPLPTLLKSL SGIDNPTHAT NKDRKRWKFQ   750
MNRFKNHKNS GSAGTDKSQR CAIM                               774