SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameFUN26
Systematic nameYAL022C
DescriptionNucleoside transporter FUN26

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP31381
SGD YAL022C
Gene Ontology (GO)
Cellular componentGO:0005622intracellularIDA:SGD.
Cellular componentGO:0016020membraneIDA:SGD.
Molecular functionGO:0005337nucleoside transporter activityIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0015858nucleoside transportIDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length517
Molecular weight58317

	---------+----------+----------+----------+----------+
MSTSADTDTI KKPILAVPEP ALADTHSEEI SRSGEEHESE NNEHSDEEGD   50
NYSEREQSVS TEPLDTLPLR KKLKNLSYIT FFAIGIGLLW PWNCILSASQ   100
YFKHDIFKDT SIWAKIFTSS MMSFSTISSM LFNIYLAKRQ YKYSRRVING   150
LVWEIIVFTV MCFFTILHFL LPKWFNFMFI MMLVVISSMG TAMTQNGIMA   200
IANVFGSEYS QGVMVGQAVA GVLPSLVLFA LAFIENSSVS TTGGILLYFF   250
TTTLVVTICV VMFSVSKISR KVNENWNVED GHITDVLLGS LRSNEEEIRI   300
VGRIDQMEDE DHRRTNGTRD DNDEGEELQL KVPFEVLFAK LKYLVLSIFT   350
TFVVTLVFPV FASATYVTGL PLSNAQYIPL IFTLWNLGDL YGRVIADWPM   400
FRDQKFTPRK TFIYSLLRVA AIPLFLMFTA ITSSSSGDEE HNGSVIVDLC   450
YMLLQFLFGV TNGHVISMSF MKVPEQLDND DEKEAAGGFT NIFVSTGLAL   500
GSIISYVFVF IIDFIIR                                       517