SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameFPS1
Systematic nameYLL043W
DescriptionGlycerol uptake/efflux facilitator protein

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP23900
SGD YLL043W
Gene Ontology (GO)
Cellular componentGO:0005886plasma membraneIDA:SGD.
Cellular componentGO:0000324vacuole, cell cycle-correlated morphologyIDA:SGD.
Molecular functionGO:0015168glycerol transporter activityIDA:SGD.
Biological processGO:0000747conjugation with cellular fusionIMP:SGD.
Biological processGO:0015793glycerol transportIDA:SGD.
Biological processGO:0046685response to arsenicIGI:SGD.
Biological processGO:0042493response to drugIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
150Phosphoserine.
168Phosphothreonine.
184Phosphothreonine.
190Phosphoserine.
212Phosphoserine.
570Phosphoserine.

Sequence Information
Sequence length669
Molecular weight73877

	---------+----------+----------+----------+----------+
MSNPQKALND FLSSESVHTH DSSRKQSNKQ SSDEGRSSSQ PSHHHSGGTN   50
NNNNNNNNNN NSNNNNNGND GGNDDDYDYE MQDYRPSPQS ARPTPTYVPQ   100
YSVESGTAFP IQEVIPSAYI NTQDINHKDN GPPSASSNRA FRPRGQTTVS   150
ANVLNIEDFY KNADDAHTIP ESHLSRRRSR SRATSNAGHS ANTGATNGRT   200
TGAQTNMESN ESPRNVPIMV KPKTLYQNPQ TPTVLPSTYH PINKWSSVKN   250
TYLKEFLAEF MGTMVMIIFG SAVVCQVNVA GKIQQDNFNV ALDNLNVTGS   300
SAETIDAMKS LTSLVSSVAG GTFDDVALGW AAAVVMGYFC AGGSAISGAH   350
LNPSITLANL VYRGFPLKKV PYYFAGQLIG AFTGALILFI WYKRVLQEAY   400
SDWWMNESVA GMFCVFPKPY LSSGRQFFSE FLCGAMLQAG TFALTDPYTC   450
LSSDVFPLMM FILIFIINAS MAYQTGTAMN LARDLGPRLA LYAVGFDHKM   500
LWVHHHHFFW VPMVGPFIGA LMGGLVYDVC IYQGHESPVN WSLPVYKEMI   550
MRAWFRRPGW KKRNRARRTS DLSDFSYNND DDEEFGERMA LQKTKTKSSI   600
SDNENEAGEK KVQFKSVQRG KRTFGGIPTI LEEEDSIETA SLGATTTDSI   650
GLSDTSSEDS HYGNAKKVT                                     669