SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameFAA4
Systematic nameYMR246W
DescriptionLong-chain-fatty-acid--CoA ligase 4

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI       
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets."
Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.
Mol Cell Proteomics. 4(6):741-51 (2005) [15699485]

Cross References
Swiss-Prot accessionP47912
SGD YMR246W
Gene Ontology (GO)
Cellular componentGO:0005811lipid particleIDA:SGD.
Molecular functionGO:0004467long-chain-fatty-acid-CoA ligase activityIDA:SGD.
Biological processGO:0006629lipid metabolic processIGI:SGD.
Biological processGO:0006869lipid transportIGI:SGD.
Biological processGO:0006499N-terminal protein myristoylationIGI:SGD.
EC number 6.2.1.3

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length694
Molecular weight77267

	---------+----------+----------+----------+----------+
MTEQYSVAVG EAANEHETAP RRNIRVKDQP LIRPINSSAS TLYEFALECF   50
TKGGKRDGMA WRDIIDIHET KKTIVKRVDG KDKPIEKTWL YYELTPYITM   100
TYEEMICVMH DIGRGLIKIG VKPNGENKFH IFASTSHKWM KTFLGCMSQG   150
IPVVTAYDTL GESGLIHSMV ETDSVAIFTD NQLLSKLAVP LKTAKNVKFV   200
IHNEPIDPSD KRQNGKLYKA AKDAVDKIKE VRPDIKIYSF DEIIEIGKKA   250
KDEVELHFPK PEDPACIMYT SGSTGTPKGV VLTHYNIVAG IGGVGHNVIG   300
WIGPTDRIIA FLPLAHIFEL TFEFEAFYWN GILGYANVKT LTPTSTRNCQ   350
GDLMEFKPTV MVGVAAVWET VRKGILAKIN ELPGWSQTLF WTVYALKERN   400
IPCSGLLSGL IFKRIREATG GNLRFILNGG SAISIDAQKF LSNLLCPMLI   450
GYGLTEGVAN ACVLEPEHFD YGIAGDLVGT ITAKLVDVED LGYFAKNNQG   500
ELLFKGAPIC SEYYKNPEET AAAFTDDGWF RTGDIAEWTP KGQVKIIDRK   550
KNLVKTLNGE YIALEKLESI YRSNPYVQNI CVYADENKVK PVGIVVPNLG   600
HLSKLAIELG IMVPGEDVES YIHEKKLQDA VCKDMLSTAK SQGLNGIELL   650
CGIVFFEEEW TPENGLVTSA QKLKRRDILA AVKPDVERVY KENT         694