SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameEGD2
Systematic nameYHR193C
DescriptionNascent polypeptide-associated complex subunit alpha

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1  UBC4, UBC5RINGSPRFMOT2   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
MethodWestern blot
Reference"The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex."
Panasenko O, Landrieux E, Feuermann M, Finka A, Paquet N, Collart MA.
J Biol Chem. 281(42):31389-98 (2006) [16926149]

Cross References
Swiss-Prot accessionP38879
SGD YHR193C
Gene Ontology (GO)
Cellular componentGO:0005854nascent polypeptide-associated complexIDA:SGD.
Molecular functionGO:0051082unfolded protein bindingIMP:SGD.
Biological processGO:0051083cotranslational protein foldingIPI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
2N-acetylserine.
58Phosphoserine.

Sequence Information
Sequence length174
Molecular weight18709

	---------+----------+----------+----------+----------+
MSAIPENANV TVLNKNEKKA RELIGKLGLK QIPGIIRVTF RKKDNQIYAI   50
EKPEVFRSAG GNYVVFGEAK VDNFTQKLAA AQQQAQASGI MPSNEDVATK   100
SPEDIQADMQ AAAEGSVNAA AEEDDEEGEV DAGDLNKDDI ELVVQQTNVS   150
KNQAIKALKA HNGDLVNAIM SLSK                               174