SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameDFM1
Systematic nameYDR411C
DescriptionDER1-like family member protein 1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ12743
SGD YDR411C
Gene Ontology (GO)
Cellular componentGO:0005783endoplasmic reticulumIDA:SGD.
Biological processGO:0030968unfolded protein responseIGI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length341
Molecular weight38131

	---------+----------+----------+----------+----------+
MAGPRNVRTL HGNGGRNNDV MGPKEFWLNI PPITRTLFTL AIVMTIVGRL   50
NLINPWYFIY VWNLTFKKVQ IWRLLTSCVM LSSRAMPALM ELYSIYDRSS   100
QLERGHFGPG LSNRRGPMVT VDYAYYLCFC ILAITTATTI IYGSYYPVVL   150
TSGFISCITY TWSIDNANVQ IMFYGLIPVW GKYFPLIQLF ISFVFNEGDF   200
VISLIGFTTG YLYTCLDTHT LGPIWGMISR KADPTYGISP NGKFSTPWWF   250
TSLYARITGA HNETATFNNN FANVPSSQRE TRTFSGRGQR LGTAPATLSQ   300
TSGTDSGRAS GSQLRSGPSN LNQFQGRGQR VGQTNSPSDS Q            341