SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Substrate Information

General Information
Standard nameDDR48
Systematic nameYMR173W
AliasFSP
DescriptionStress protein DDR48

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI    RPN10 Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets."
Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.
Mol Cell Proteomics. 4(6):741-51 (2005) [15699485]

Cross References
Swiss-Prot accessionP18899
SGD YMR173W
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
Molecular functionGO:0016887ATPase activityIDA:SGD.
Molecular functionGO:0003924GTPase activityIDA:SGD.
Biological processGO:0006281DNA repairIDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
319Phosphoserine.
322Phosphoserine.
327Phosphoserine.
330Phosphoserine.

Sequence Information
Sequence length430
Molecular weight46233

	---------+----------+----------+----------+----------+
MGLFDKVKQF ANSNNNNNDS GNNNQGDYVT KAENMIGEDR VNQFKSKIGE   50
DRFDKMESKV RQQFSNTSIN DNDSNNNDSY GSNNNDSYGS NNNDSYGSNN   100
NDSYGSNNND SYGSNNDDSY GSSNKKKSSY GSNNDDSYGS SNNNDSYGSN   150
NNDSYGSNNN DSYGSNNDDS YGSSNKNKSS YGSNNDDSYG SNNDDSYGSS   200
NKKKSSYGSS NNDSYGSNND DSYGSNNNDS YGSNNDDSYG SSNKKKSSYG   250
SNNDDSYGSS NNNDSYGSNN DDSYGSSNKN KSSYGSSSND DSYGSSNNDD   300
SYGSSNKKKS SYGSNNDDSY GSNNDDSYGS SNKKKSSYGS SNNDSYGSNN   350
DDSYGSSNKK KSSYGSNNDD SYGSSNNNDS YGSNNDDSYG SSNRNKNSYG   400
SSNYGSSNND DSYGSSNRGG RNQYGGDDDY                          430