SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCYK2
Systematic nameYMR032W
AliasHOF1
DescriptionCytokinesis 2 protein

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1  CDC34RINGSCFGRR1  Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidenceProtein Stability Assay
MethodWestern blot
Reference"Degradation of Hof1 by SCF(Grr1) is important for actomyosin contraction during cytokinesis in yeast."
Blondel M, Bach S, Bamps S, Dobbelaere J, Wiget P, Longaretti C, Barral Y, Meijer L, Peter M.
EMBO J. 24(7):1440-52 (2005) [15775961]

Cross References
Swiss-Prot accessionQ05080
SGD YMR032W
Gene Ontology (GO)
Cellular componentGO:0000142cellular bud neck contractile ringIDA:SGD.
Molecular functionGO:0008092cytoskeletal protein bindingIPI:SGD.
Biological processGO:0000910cytokinesisIMP:SGD.
Biological processGO:0006974response to DNA damage stimulusIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length669
Molecular weight76207

	---------+----------+----------+----------+----------+
MSYSYEACFW DPNDNGVNIL LGHISQGIRS CDSMILFFKQ RSELEKDYAR   50
RLGAITGKLD KDIGTNMDYG KLNETFNVVL SVEKARAQSH SKQSEILFRQ   100
IYTDTKAFAA NLQARYTTLS GKIERLRMDK FNKKKGCEVL QKKLQDAQIR   150
FRDLQLNENN MIGAKRVEHN KRELLKWESN SQEYKVQLDV LKQEYKASQK   200
FWIHEWAQLS CELQEMENAR ISFLQSKLQQ FATSSMETYI LEQTKMDMLT   250
NHLNSFTAAD EISTFSKENG TGRLKHKTSK GDMNSSANWA QMSSISTTSK   300
KTESYMDNIR KLSSQLKETE NKRKLASIDK YEKPLPSPEV TMATQFRNST   350
PVIRNETKVV ANPTLSLRSS PVQLQSNVDD SVLRQKPDKP RPIVGEEQLK   400
PDEDSKNPDE KGLMVHKRNQ SLSSPSESSS SNPTDFSHIK KRQSMESMTT   450
SVSSMANSID DSQRFAKSWN SSNRKRKSMS HLQVPSSASS RSDDGGRTPN   500
SAHNLNEDDY NTRRDTSTST ILFKPPVAVR GTSRGHTHRQ SMIMQDSSNP   550
IEDALYEMER IQSSSKPGTK TGNIMDERGV VRDRGITVTL PIVTSEGFPV   600
IEYAKAMYPL IGNEAPGLAN FHKGDYLLIT EIVNKDWYKG EVYDNDRIDR   650
NHRIGLIPYN FIQLLHQGL                                     669