SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCUP9
Systematic nameYPL177C
DescriptionHomeobox protein CUP9

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1  RAD6, UBC4RINGSPRFUBR1   
2 MULTIRAD6RINGSPRFUBR1   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceProtein Stability Assay
MethodWestern blot
Reference"The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor."
Byrd C, Turner GC, Varshavsky A.
EMBO J. 17(1):269-77 (1998) [9427760]
[2]EvidenceHigh MW Product Confirmation
Methodautoradiography (in vitro)
Reference"Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway."
Turner GC, Du F, Varshavsky A.
Nature. 405(6786):579-83 (2000) [10850718]

Cross References
Swiss-Prot accessionP41817
SGD YPL177C
Gene Ontology (GO)
Biological processGO:0006878copper ion homeostasisIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length306
Molecular weight34654

	---------+----------+----------+----------+----------+
MNYNCEIQNR NSKNVDNQVS LPPIQVLFNS IEKRSMPELA FSNIEYSHGN   50
LRSSTEEQNY PAPVLLPQHH SIAYPAINSG GTSTTATPTA STVETSKTSS   100
SAMDTQSQYG SSKKSKSASD DAKPCYKSAP IYEIINKEKD AGAQYNRPFS   150
DFVESKSRRK QNSGRRSNLP KETVQILNTW LLNHLNNPYP TQQEKRELLI   200
KTGLTKIQLS NWFINVRRRK IFSDYYTLVN SIPNDNANNT PVERVQNVSA   250
YHNTLSATNN TMYDATSTCS TDYELSKRFA HAPVTRRKKL IDRLEELKKL   300
SNPDMN                                                   306