SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCTR1
Systematic nameYPR124W
DescriptionCopper transport protein CTR1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1K340;K345  HECTNARSP5  Vacuolar Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
MethodWestern blot
Reference"Regulation of Copper-Dependent Endocytosis and Vacuolar Degradation of the Yeast Copper Transporter, Ctr1p, by the Rsp5 Ubiquitin Ligase."
Liu J, Sitaram A, Burd CG.
Traffic. 8(10):1375-84 (2007) [17645432]

Cross References
Swiss-Prot accessionP49573
SGD YPR124W
Gene Ontology (GO)
Cellular componentGO:0005886plasma membraneIDA:SGD.
Molecular functionGO:0015088copper uptake transporter activityIMP:SGD.
Molecular functionGO:0042802identical protein bindingIPI:IntAct.
Biological processGO:0015677copper ion importIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
344Phosphoserine.
356Phosphothreonine.
369Phosphoserine.

Sequence Information
Sequence length406
Molecular weight44442

	---------+----------+----------+----------+----------+
MEGMNMGSSM NMDAMSSASK TVASSMASMS MDAMSSASKT ILSSMSSMSM   50
EAMSSASKTL ASTMSSMASM SMGSSSMSGM SMSMSSTPTS SASAQTTSDS   100
SMSGMSGMSS SDNSSSSGMD MDMSMGMNYY LTPTYKNYPV LFHHLHANNS   150
GKAFGIFLLF VVAAFVYKLL LFVSWCLEVH WFKKWDKQNK YSTLPSANSK   200
DEGKHYDTEN NFEIQGLPKL PNLLSDIFVP SLMDLFHDII RAFLVFTSTM   250
IIYMLMLATM SFVLTYVFAV ITGLALSEVF FNRCKIAMLK RWDIQREIQK   300
AKSCPGFGNC QCGRHPEPSP DPIAVADTTS GSDQSTRLEK NNESKVAISE   350
NNQKKTPTQE EGCNCATDSG KNQANIERDI LENSKLQEQS GNMDQNLLPA   400
EKFTHN                                                   406

	* Ubiquitinated lysine is denoted as red color.