SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCTH1
Systematic nameYDR151C
DescriptionZinc finger protein CTH1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI    RPN10 Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP47976
SGD YDR151C
Gene Ontology (GO)
Cellular componentGO:0005634nucleusIC:SGD.
Biological processGO:0006879iron ion homeostasisIGI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length325
Molecular weight36772

	---------+----------+----------+----------+----------+
MMPNVAPNSY YLNIPNANST STTTSSIFSD LNKEYESKIK EIEEYYIKTL   50
LNENTDNDDS SSSEGHNINE TDILSEYSPR PSPWLPSKPN CYHPLGDFKD   100
LIISDSRPTN TLPINNPFAG NNNISTLATT EKKRKKRSLE VEINPTYTTS   150
AFSLPLTAEN LQKLSQVDSQ STGLPYTLPI QKTTKLEPCR RAPLQLPQLV   200
NKTLYKTELC ESFTIKGYCK YGNKCQFAHG LNELKFKKKS NNYRTKPCIN   250
WSKLGYCPYG KRCCFKHGDD KDVEIYQNAN DGRSKDTALT PLPTSLAPSN   300
NDNITNLSKP RNLHTSVKAL QRMTW                              325