SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCOY1
Systematic nameYKL179C
DescriptionProtein CASP

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP34237
SGD YKL179C
Gene Ontology (GO)
Cellular componentGO:0000139Golgi membraneIGI:SGD.
Biological processGO:0048193Golgi vesicle transportIGI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
364Phosphoserine.
450Phosphoserine.
463Phosphothreonine.

Sequence Information
Sequence length679
Molecular weight77514

	---------+----------+----------+----------+----------+
MDTSVYSHAL DIWAKADLTN LQRELDADVI EIKDKETLSL NSRKSLATET   50
KKFKKLEPEE KLNNVNKIIK QYQREIDNLT QRSKFSEKVL FDVYEKLSEA   100
PDPQPLLQSS LEKLGKIDDS KELKEKISYL EDKLAKYADY ETLKSRLLDL   150
EQSSAKTLAK RLTAKTQEIN STWEEKGRNW KEREADLLKQ LTNVQEQNKA   200
LEAKISKNID IEGNGNEDGD QENNQKEVST RIAEYNLVTQ ELETTQARIY   250
QLEKRNEELS GALAKATSEA EKETELHAKE LKLNQLESEN ALLSASYEQE   300
RKSTSHAINE LKEQLNSVVA ESESYKSELE TVRRKLNNYS DYNKIKEELS   350
ALKKIEFGVN EDDSDNDIRS EDKNDNTFES SLLSANKKLQ ATLAEYRSKS   400
TAQEEERNEL KKSVDQLKQQ IATLKEANEK LETDLEKVEN VSPHFNETAS   450
MMSGVTRQMN NRTSHKMSPT SSIIGIPEDG ELSGNQSTIL PIVTKQRDRF   500
RSRNMDLEKQ LRQGNSEKGK LKLEISKLKG DNTKLYERIR YLQSYNNNNA   550
PVNQSTERID VESQYSRVYD ESLHPMANFR QNELNHYKNK KLSALEKLFS   600
SFAKVILQNK MTRMVFLFYC IGLHGLVFMM SMYVINISGY MTPEVGIVQS   650
AKSSSNLNGG LGGAEKVAAG VGSVHGINR                          679