SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCIN8
Systematic nameYEL061C
AliasKSL2
DescriptionKinesin-like protein CIN8

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1   RINGAPCCDH1   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceProtein Stability Assay
MethodWestern blot
Reference"Cell cycle-dependent degradation of the Saccharomyces cerevisiae spindle motor Cin8p requires APC(Cdh1) and a bipartite destruction sequence."
Hildebrandt ER, Hoyt MA.
Mol Biol Cell. 12(11):3402-16 (2001) [11694576]

Cross References
Swiss-Prot accessionP27895
SGD YEL061C
Gene Ontology (GO)
Cellular componentGO:0000778condensed nuclear chromosome kinetochoreIDA:SGD.
Cellular componentGO:0005871kinesin complexTAS:SGD.
Cellular componentGO:0005739mitochondrionIDA:SGD.
Cellular componentGO:0005876spindle microtubuleIDA:SGD.
Molecular functionGO:0003777microtubule motor activityTAS:SGD.
Biological processGO:0000092mitotic anaphase BIMP:SGD.
Biological processGO:0000070mitotic sister chromatid segregationTAS:SGD.
Biological processGO:0030472mitotic spindle organization and biogenesis...TAS:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length1000
Molecular weight113311

	---------+----------+----------+----------+----------+
MPAENQNTGQ DRSSNSISKN GNSQVGCHTV PNEELNITVA VRCRGRNERE   50
ISMKSSVVVN VPDITGSKEI SINTTGDTGI TAQMNAKRYT VDKVFGPGAS   100
QDLIFDEVAG PLFQDFIKGY NCTVLVYGMT STGKTYTMTG DEKLYNGELS   150
DAAGIIPRVL LKLFDTLELQ QNDYVVKCSF IELYNEELKD LLDSNSNGSS   200
NTGFDGQFMK KLRIFDSSTA NNTTSNSASS SRSNSRNSSP RSLNDLTPKA   250
ALLRKRLRTK SLPNTIKQQY QQQQAVNSRN NSSSNSGSTT NNASSNTNTN   300
NGQRSSMAPN DQTNGIYIQN LQEFHITNAM EGLNLLQKGL KHRQVASTKM   350
NDFSSRSHTI FTITLYKKHQ DELFRISKMN LVDLAGSENI NRSGALNQRA   400
KEAGSINQSL LTLGRVINAL VDKSGHIPFR ESKLTRLLQD SLGGNTKTAL   450
IATISPAKVT SEETCSTLEY ASKAKNIKNK PQLGSFIMKD ILVKNITMEL   500
AKIKSDLLST KSKEGIYMSQ DHYKNLNSDL ESYKNEVQEC KREIESLTSK   550
NALLVKDKLK SKETIQSQNC QIESLKTTID HLRAQLDKQH KTEIEISDFN   600
NKLQKLTEVM QMALHDYKKR ELDLNQKFEM HITKEIKKLK STLFLQLNTM   650
QQESILQETN IQPNLDMIKN EVLTLMRTMQ EKAELMYKDC VKKILNESPK   700
FFNVVIEKID IIRVDFQKFY KNIAENLSDI SEENNNMKQY LKNHFFKNNH   750
QELLNRHVDS TYENIEKRTN EFVENFKKVL NDHLDENKKL IMQNLTTATS   800
AVIDQEMDLF EPKRVKWENS FDLINDCDSM NNEFYNSMAA TLSQIKSTVD   850
TSSNSMNESI SVMKGQVEES ENAISLLKNN TKFNDQFEQL INKHNMLKDN   900
IKNSITSTHS HITNVDDIYN TIENIMKNYG NKENATKDEM IENILKEIPN   950
LSKKMPLRLS NINSNSVQSV ISPKKHAIED ENKSSENVDN EGSRKMLKIE   1000