SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCCT2
Systematic nameYIL142W
AliasBIN3, TCP2
DescriptionT-complex protein 1 subunit beta

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP39076
SGD YIL142W
Gene Ontology (GO)
Cellular componentGO:0005832chaperonin-containing T-complexIPI:SGD.
Cellular componentGO:0005856cytoskeletonTAS:SGD.
Molecular functionGO:0051082unfolded protein bindingTAS:SGD.
Biological processGO:0007010cytoskeleton organization and biogenesisTAS:SGD.
Biological processGO:0006457protein foldingTAS:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
254Phosphoserine.

Sequence Information
Sequence length527
Molecular weight57203

	---------+----------+----------+----------+----------+
MSVQIFGDQV TEERAENARL SAFVGAIAVG DLVKSTLGPK GMDKLLQSAS   50
SNTCMVTNDG ATILKSIPLD NPAAKVLVNI SKVQDDEVGD GTTSVTVLSA   100
ELLREAEKLI DQSKIHPQTI IEGYRLASAA ALDALTKAAV DNSHDKTMFR   150
EDLIHIAKTT LSSKILSQDK DHFAELATNA ILRLKGSTNL EHIQIIKILG   200
GKLSDSFLDE GFILAKKFGN NQPKRIENAK ILIANTTLDT DKVKIFGTKF   250
KVDSTAKLAQ LEKAEREKMK NKIAKISKFG INTFINRQLI YDYPEQLFTD   300
LGINSIEHAD FEGVERLALV TGGEVVSTFD EPSKCKLGEC DVIEEIMLGE   350
QPFLKFSGCK AGEACTIVLR GATDQTLDEA ERSLHDALSV LSQTTKETRT   400
VLGGGCAEMV MSKAVDTEAQ NIDGKKSLAV EAFARALRQL PTILADNAGF   450
DSSELVSKLR SSIYNGISTS GLDLNNGTIA DMRQLGIVES YKLKRAVVSS   500
ASEAAEVLLR VDNIIRARPR TANRQHM                            527