SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCCH1
Systematic nameYGR217W
DescriptionCalcium-channel protein CCH1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP50077
SGD YGR217W
Gene Ontology (GO)
Cellular componentGO:0005886plasma membraneIDA:SGD.
Molecular functionGO:0005262calcium channel activityIDA:SGD.
Biological processGO:0006816calcium ion transportIDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
284Phosphoserine.

Sequence Information
Sequence length2039
Molecular weight234599

	---------+----------+----------+----------+----------+
MQGRKRTLTE PFEPNTNPFG DNAAVMTENV EDNSETDGNR LESKPQALVP   50
PALNIVPPES SIHSTEEKKG DEYNGNDKDS SLISNIFRTR VGRSSHENLS   100
RPKLSLKTAS FGAAESSRRN VSPSTKSAKS SSQYIDLNDE RLRRRSFSSY   150
SRSSSRRVSN SPSSTDRPPR SAKVLSLIAA DDMDDFEDLQ KGFKSAIDEE   200
GLTWLPQLKS EKSRPVSDVG EDRGEGEQES IPDVHTPNVG ASATPGSIHL   250
TPEPAQNGSV SEGLEGSINN SRKKPSPKFF HHLSPQKEDK DQTEVIEYAE   300
DILDFETLQR KLESRPFVLY GHSLGVFSPT NPLRIKIARF LLHRRYSLLY   350
NTLLTFYAIL LAIRTYNPHN VVFLYRFSNW TDYFIFILSA CFTGNDIAKI   400
IAFGFWDDSE MFKAYGREYK SILQRSGIMK LYIYLREKYG RKLIDFIIPF   450
RIISPGEETK YQRSSLSTSL TKPYGAKENQ RPFGTPRAFA RSSWNRIDLV   500
SSVSFWLGMF LSIKSYDTKT GIRIFKPLAI LRILRLVNVD TGMPSILRGL   550
KYGIPQLVNV SSMLVYFWIF FGILGVQIFQ GSFRRQCVWF NPEDPTDTYQ   600
YDMQFCGGYL DPVTKRKQNY IYEDGSEGSV SKGFLCPQYS KCVSNANPYN   650
GRISFDNIVN SMELVFVIMS ANTFTDLMYY TMDSDEMAAC LFFIVCIFVL   700
TIWLLNLLIA VLVSSFEIAN EEYKKKKFIY GSRKTGYVAR IVTGYWKYFK   750
LKANQTKFPN WSQKGLAIYS HVEFIFVILI ICDIGMRASV KVSTSANCNN   800
ILLKTDRGIS IVLFIESLAR LVLYLPNMWK FLTKPSYVYD FIISIITLVI   850
SCLAVEGVLG HMYAWLSIFH ISRFYRVIIS FNLTKKLWKQ ILSNGVMIWN   900
LSSFYFFFTF LVAIIMAVYF EGVIPPEEMA DQPFGMYSLP NSFLSLFIIG   950
STENWTDILY ALQKHSPNIS STFFCSVFFI IWFLLSNSVI LNIFIALISE   1000
SMEVKEEEKR PQQIKHYLKF VYPQKIQEYT HASLVARIRK KFFGGHRNED   1050
TRDFKQFLMR GTAIMNIAQN MGELADEFKE PPSENLFKKG LSKLTIGVPS   1100
LKRLRMFANN PFYKNSDVVF TETNDINGRT YILELNEYED EKLDYLKKYP   1150
LFNYSYYFFS PQHRFRRFCQ RLVPPSTGKR TDGSRFFEDS TDLYNKRSYF   1200
HHIERDVFVF IFALATILLI VCSCYVTPLY RMHHKMGTWN WSSALDCAFI   1250
GAFSIEFIVK TVADGFIYSP NAYLRNPWNF IDFCVLISMW INLIAYLKNN   1300
GNLSRIFKGL TALRALRCLT ISNTARQTFN LVMFDGLNKI FEAGLISLSL   1350
LFPFTVWGLS IFKGRLGTCN DGSLGRADCY NEYSNSVFQW DIMSPRVYQQ   1400
PYLHLDSFAS AFSSLYQIIS LEGWVDLLEN MMNSSGIGTP ATVMGSAGNA   1450
LFLVLFNFLS MVFILNLFVS FIVNNQARTT GSAYFTIEEK AWLESQKLLS   1500
QAKPKAIPNL IELSRVRQFF YQLAVEKKNF YYASFLQVVL YLHIIMLLSR   1550
SYNPGNLIGY QGVYFMFSTS VFLIQEALHM CGEGPRLYFR QKWNSIRLSI   1600
IIIAFIMNAV AFHVPASHYW FHNIKGFFLL VIFLFIIPQN DTLTELLETA   1650
MASLPPILSL TYTWGVLFLV YAIALNQIFG LTRLGSNTTD NINFRTVIKS   1700
MIVLFRCSFG EGWNYIMADL TVSEPYCSSD DNSTYTDCGS ETYAYLLLMS   1750
WNIISMYIFV NMFVSLIIGN FSYVYRSGGS RSGINRSEIK KYIEAWSKFD   1800
TDGTGELELS YLPRIMHSFD GPLSFKIWEG RLTIKSLVEN YMEVNPDDPY   1850
DVKIDLIGLN KELNTIDKAK IIQRKLQYRR FVQSIHYTNA YNGCIRFSDL   1900
LLQIPLYTAY SARECLGIDQ YVHHLYILGK VDKYLENQRN FDVLEMVVTR   1950
WKFHCRMKRT IEPEWDVKDP TVSSHISNIN VNLEPAPGIL EREPIATPRM   2000
DYGVNNFMWS PRMNQDSTME PPEEPIDNND DSANDLIDR               2039