SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameCBR1
Systematic nameYIL043C
AliasCBR, CBR5
DescriptionNADH-cytochrome b5 reductase 1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI       
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets."
Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.
Mol Cell Proteomics. 4(6):741-51 (2005) [15699485]

Cross References
Swiss-Prot accessionP38626
SGD YIL043C
Gene Ontology (GO)
Cellular componentGO:0005792microsomeIDA:SGD.
Cellular componentGO:0005741mitochondrial outer membraneIDA:SGD.
Molecular functionGO:0004128cytochrome-b5 reductase activityIDA:SGD.
Biological processGO:0006118electron transportIDA:SGD.
EC number 1.6.2.2

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length322
Molecular weight36199

	---------+----------+----------+----------+----------+
MYKYSYYIRR KNEREKKVLK VCIQLALQQE TQSIKQSKMA IDAQKLVVVI   50
VIVVVPLLFK FIIGPKTKPV LDPKRNDFQS FPLVEKTILT HNTSMYKFGL   100
PHADDVLGLP IGQHIVIKAN INGKDITRSY TPTSLDGDTK GNFELLVKSY   150
PTGNVSKMIG ELKIGDSIQI KGPRGNYHYE RNCRSHLGMI AGGTGIAPMY   200
QIMKAIAMDP HDTTKVSLVF GNVHEEDILL KKELEALVAM KPSQFKIVYY   250
LDSPDREDWT GGVGYITKDV IKEHLPAATM DNVQILICGP PAMVASVRRS   300
TVDLGFRRSK PLSKMEDQVF VF                                 322