SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameBTN2
Systematic nameYGR142W
DescriptionProtein BTN2

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP53286
SGD YGR142W
Gene Ontology (GO)
Cellular componentGO:0005829cytosolIDA:SGD.
Cellular componentGO:0005770late endosomeIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0006865amino acid transportIMP:SGD.
Biological processGO:0006886intracellular protein transportIMP:SGD.
Biological processGO:0006885regulation of pHIMP:SGD.
Biological processGO:0042147retrograde transport, endosome to GolgiIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
379Phosphoserine.

Sequence Information
Sequence length410
Molecular weight47168

	---------+----------+----------+----------+----------+
MFSIFNSPCV FEQLPSFSQP LHSRYFDCSS PVSYYPECKR RKAIKANLRA   50
PKKSDANCSE PLRYALAETP NGYTLSLSKR IPYELFSKYV NEKLGELKEN   100
HYRPTYHVVQ DFFGNQYYVE DEADEDALLR SALKDLDFRA IGKKIAKDLF   150
QDYEIELNHR GDELSILSKK DKIFKEFSLD QVFEDVFVIG CGVENIDDGS   200
REKYALLKIG LVKHEEEISE GGINEPKMPI IESKIDESHD DVNMSESLKE   250
EEAEKAKEPL TKEDQIKKWI EEERLMQEES RKSEQEKAAK EDEERQKKEK   300
EARLKARKES LINKQKTKRS QQKKLQNSKS LPISEIEASN KNNNSNSGSA   350
ESDNESINSD SDTTLDFSVS GNTLKKHASP LLEDVEDEEV DRYNESLSRS   400
PKGNSIIEEI                                                410