SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameAUR1
Systematic nameYKL004W
DescriptionAureobasidin A resistance protein

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP36107
SGD YKL004W
Gene Ontology (GO)
Cellular componentGO:0005794Golgi apparatusIDA:SGD.
Molecular functionGO:0045140inositol phosphoceramide synthase activityIDA:SGD.
Biological processGO:0006665sphingolipid metabolic processIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
392Phosphoserine.
395Phosphoserine.

Sequence Information
Sequence length401
Molecular weight45193

	---------+----------+----------+----------+----------+
MANPFSRWFL SERPPNCHVA DLETSLDPHQ TLLKVQKYKP ALSDWVHYIF   50
LGSIMLFVFI TNPAPWIFKI LFYCFLGTLF IIPATSQFFF NALPILTWVA   100
LYFTSSYFPD DRRPPITVKV LPAVETILYG DNLSDILATS TNSFLDILAW   150
LPYGLFHFGA PFVVAAILFV FGPPTVLQGY AFAFGYMNLF GVIMQNVFPA   200
APPWYKILYG LQSANYDMHG SPGGLARIDK LLGINMYTTA FSNSSVIFGA   250
FPSLHSGCAT MEALFFCYCF PKLKPLFIAY VCWLWWSTMY LTHHYFVDLM   300
AGSVLSYVIF QYTKYTHLPI VDTSLFCRWS YTSIEKYDIS KSDPLAADSN   350
DIESVPLSNL ELDFDLNMTD EPSVSPSLFD GSTSVSRSSA TSITSLGVKR   400
A                                                        401