SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameARO3
Systematic nameYDR035W
DescriptionPhospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (HB-ubiquitin (a tandem affinity tag under denaturing conditions)), LC/MS
Reference"A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking."
Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P.
Mol Cell Proteomics. 5(4):737-48 (2006) [16432255]

Cross References
Swiss-Prot accessionP14843
SGD YDR035W
Gene Ontology (GO)
Cellular componentGO:0005739mitochondrionIDA:SGD.
Cellular componentGO:0005634nucleusIDA:SGD.
Molecular functionGO:00038493-deoxy-7-phosphoheptulonate synthase activityIDA:SGD.
EC number 2.5.1.54

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
26Phosphothreonine.

Sequence Information
Sequence length370
Molecular weight41070

	---------+----------+----------+----------+----------+
MFIKNDHAGD RKRLEDWRIK GYDPLTPPDL LQHEFPISAK GEENIIKARD   50
SVCDILNGKD DRLVIVIGPC SLHDPKAAYD YADRLAKISE KLSKDLLIIM   100
RAYLEKPRTT VGWKGLINDP DMNNSFQINK GLRISREMFI KLVEKLPIAG   150
EMLDTISPQF LSDCFSLGAI GARTTESQLH RELASGLSFP IGFKNGTDGG   200
LQVAIDAMRA AAHEHYFLSV TKPGVTAIVG TEGNKDTFLI LRGGKNGTNF   250
DKESVQNTKK QLEKAGLTDD SQKRIMIDCS HGNSNKDFKN QPKVAKCIYD   300
QLTEGENSLC GVMIESNINE GRQDIPKEGG REGLKYGCSV TDACIGWEST   350
EQVLELLAEG VRNRRKALKK                                     370