SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameAPE3
Systematic nameYBR286W
DescriptionAminopeptidase Y

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (HB-ubiquitin (a tandem affinity tag under denaturing conditions)), LC/MS
Reference"A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking."
Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P.
Mol Cell Proteomics. 5(4):737-48 (2006) [16432255]

Cross References
Swiss-Prot accessionP37302
SGD YBR286W
Gene Ontology (GO)
Cellular componentGO:0000324vacuole, cell cycle-correlated morphologyIDA:SGD.
Molecular functionGO:0004177aminopeptidase activityIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0000723telomere maintenanceIMP:SGD.
Biological processGO:0007039vacuolar protein catabolic processIDA:SGD.
EC number 3.4.11.15

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length537
Molecular weight60137

	---------+----------+----------+----------+----------+
MHFSLKQLAV AAFYATNLGS AYVIPQFFQE AFQQEEPIEN YLPQLNDDDS   50
SAVAANIPKP HIPYFMKPHV ESEKLQDKIK VDDLNATAWD LYRLANYSTP   100
DYGHPTRVIG SKGHNKTMEY ILNVFDDMQD YYDVSLQEFE ALSGKIISFN   150
LSDAETGKSF ANTTAFALSP PVDGFVGKLV EIPNLGCEEK DYASVVPPRH   200
NEKQIALIER GKCPFGDKSN LAGKFGFTAV VIYDNEPKSK EGLHGTLGEP   250
TKHTVATVGV PYKVGKKLIA NIALNIDYSL YFAMDSYVEF IKTQNIIADT   300
KHGDPDNIVA LGAHSDSVEE GPGINDDGSG TISLLNVAKQ LTHFKINNKV   350
RFAWWAAEEE GLLGSNFYAY NLTKEENSKI RVFMDYDMMA SPNYEYEIYD   400
ANNKENPKGS EELKNLYVDY YKAHHLNYTL VPFDGRSDYV GFINNGIPAG   450
GIATGAEKNN VNNGKVLDRC YHQLCDDVSN LSWDAFITNT KLIAHSVATY   500
ADSFEGFPKR ETQKHKEVDI LNAQQPQFKY RADFLII                 537