SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameAKR1
Systematic nameYDR264C
DescriptionPalmitoyltransferase AKR1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionP39010
SGD YDR264C
Gene Ontology (GO)
Cellular componentGO:0016020membraneIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Molecular functionGO:0019706protein-cysteine S-palmitoleyltransferase a...IDA:SGD.
Biological processGO:0006897endocytosisIMP:SGD.
Biological processGO:0000750pheromone-dependent signal transduction dur...IGI:SGD.
Biological processGO:0018318protein amino acid palmitoylationIDA:SGD.
Biological processGO:0006612protein targeting to membraneIMP:SGD.
EC number 2.3.1.-

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
51Phosphoserine.
57Phosphoserine.

Sequence Information
Sequence length764
Molecular weight85840

	---------+----------+----------+----------+----------+
MVNELENVPR ASTLTNEEQT VDPSNNDSQE DISLGDSNEI TSLASLKAIR   50
SGNEEESGNE QVNHNDEAEE DPLLTRYHTA CQRGDLATVK EMIHGKLLEV   100
NNDGDSTEHI TGLHWASINN RLSVVDFLVS QGADVNARAG ALHATPLHWA   150
ARYGYVYIVD FLLKHGADPT MTDDQGFNLL HLSVNSSNIM LVLYVLFNVV   200
SKGLLDIDCR DPKGRTSLLW AAYQGDSLTV AELLKFGASI KIADTEGFTP   250
LHWGTVKGQP HVLKYLIQDG ADFFQKTDTG KDCFAIAQEM NTVYSLREAL   300
THSGFDYHGY PIKKWFKKSQ HAKLVTFITP FLFLGIAFAL FSHINPLFVI   350
IVLFLLAIAT NKGLNKFVLP SYGRMGVHNV TLLRSPLLSG VFFGTLLWVT   400
IVWFFKVMPR TFSDEQYTNI LMLVILVSVF YLFGQLVIMD PGCLPEETDH   450
ENVRQTISNL LEIGKFDTKN FCIETWIRKP LRSKFSPLNN AVVARFDHYC   500
PWIFNDVGLK NHKAFIFFIT LMESGIFTFL ALCLEYFDEL EDAHEDTSQK   550
NGKCFILGAS DLCSGLIYDR FVFLILLWAL LQSIWVASLI FVQAFQICKG   600
MTNTEFNVLM KESKSIGPDG LSFNENFNTT PEGFAPSIDP GEESNDTVLA   650
PVPGSTIRKP RTCFGVCYAV TGMDQWLAVI KETIGIKDST GHNVYSITSR   700
IPTNYGWKRN VKDFWLTSDI NAPLWRRILY PPSGSKALLN GIEVDYFKLY   750
KLPNKDVEQG NDMV                                          764