SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameAHA1
Systematic nameYDR214W
DescriptionHsp90 co-chaperone AHA1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (HB-ubiquitin (a tandem affinity tag under denaturing conditions)), LC/MS
Reference"A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking."
Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P.
Mol Cell Proteomics. 5(4):737-48 (2006) [16432255]

Cross References
Swiss-Prot accessionQ12449
SGD YDR214W
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIPI:SGD.
Molecular functionGO:0001671ATPase activator activityIDA:UniProtKB.
Molecular functionGO:0030189chaperone activator activityIDA:SGD.
Molecular functionGO:0051087chaperone bindingIDA:SGD.
Biological processGO:0006457protein foldingIMP:SGD.
Biological processGO:0006950response to stressIEP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
172Phosphoserine.

Sequence Information
Sequence length350
Molecular weight39436

	---------+----------+----------+----------+----------+
MVVNNPNNWH WVDKNCIGWA KEYFKQKLVG VEAGSVKDKK YAKIKSVSSI   50
EGDCEVNQRK GKVISLFDLK ITVLIEGHVD SKDGSALPFE GSINVPEVAF   100
DSEASSYQFD ISIFKETSEL SEAKPLIRSE LLPKLRQIFQ QFGKDLLATH   150
GNDIQVPESQ VKSNYTRGNQ KSSFTEIKDS ASKPKKNALP SSTSTSAPVS   200
STNKVPQNGS GNSTSIYLEP TFNVPSSELY ETFLDKQRIL AWTRSAQFFN   250
SGPKLETKEK FELFGGNVIS ELVSCEKDKK LVFHWKLKDW SAPFNSTIEM   300
TFHESQEFHE TKLQVKWTGI PVGEEDRVRA NFEEYYVRSI KLTFGFGAVL   350