SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameADE6
Systematic nameYGR061C
DescriptionPhosphoribosylformylglycinamidine synthase

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (HB-ubiquitin (a tandem affinity tag under denaturing conditions)), LC/MS
Reference"A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking."
Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P.
Mol Cell Proteomics. 5(4):737-48 (2006) [16432255]

Cross References
Swiss-Prot accessionP38972
SGD YGR061C
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
Molecular functionGO:0042802identical protein bindingIPI:IntAct.
Molecular functionGO:0004642phosphoribosylformylglycinamidine synthase ...TAS:SGD.
Biological processGO:0006164purine nucleotide biosynthetic processIMP:SGD.
EC number 6.3.5.3

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length1358
Molecular weight148905

	---------+----------+----------+----------+----------+
MTDYILPGPK ALSQFRVDNL IKDINSYTNS TSVINELRSC YIHYVNGIAQ   50
NLSEQDTKLL EVLLTYDSAL DIANDPLARQ LNDAVANNLP SSALGEDTYL   100
IRVVPRSGTI SPWSSKATNI AHVCGLQDKV QRIERGLALL IKTVPGFPLL   150
ENLNDISLKC VYDRMTQQLY LTEPPNTMSI FTHEEPKPLV HVPLTPKDTK   200
QSPKDILSKA NTELGLALDS GEMEYLIHAF VETMKRDPTD VELFMFAQVN   250
SEHCRHKIFN ADWTIDGIKQ QFTLFQMIRN THKLNPEYTI SAYSDNAAVL   300
DSENDAFFFA PNSTTKEWTS TKERIPLLIK VETHNHPTAV SPFPGAATGS   350
GGEIRDEGAT GRGSKTKCGL SGFSVSDLLI PGNEQPWELN IGKPYHIASA   400
LDIMIEAPLG SAAFNNEFGR PCINGYFRTL TTKVLNHQGK EEIRGFHKPI   450
MIAGGFGTVR PQFALKNTPI TPGSCLIVLG GQSMLIGLGG GAASSVASGE   500
GSADLDFASV QRGNPEMERR CQQVIDACVA LGNNNPIQSI HDVGAGGLSN   550
ALPELVHDND LGAKFDIRKV LSLEPGMSPM EIWCNESQER YVLGVSPQDL   600
SIFEEICKRE RAPFAVVGHA TAEQKLIVED PLLKTTPIDL EMPILFGKPP   650
KMSRETITEA LNLPEANLSE IPSLQDAIQR VLNLPSVGSK SFLITIGDRS   700
VTGLIDRDQF VGPWQVPVAD VGVTGTSLGE TIISTGEAMA MGEKPVNALI   750
SASASAKLSV AESLLNIFAA DVKSLNHIKL SANWMSPASH QGEGSKLYEA   800
VQALGLDLCP ALGVAIPVGK DSMSMKMKWD DKEVTAPLSL NITAFAPVFN   850
TSKTWTPLLN RNTDDSVLVL VDLSAKQETK SLGASALLQV YNQVGNKSPT   900
VYDNAILKGF LESLIQLHQQ KEDIVLAYHD RSDGGLLITL LEMAFASRCG   950
LEINIDGGDL ESQLTNLFNE ELGAVFQISA KNLSKFEKIL NENGVAKEYI   1000
SIVGKPSFQS QEIKIINSTT NDVIYANSRS ELEQTWSKTS YEMQKLRDNP   1050
KTAEEEFASI TDDRDPGLQY ALTYNPADDM KIGLELSSQR PKVAILREQG   1100
VNGQMEMAWC FQQAGFNSVD VTMTDLLEGR FHLDDFIGLA ACGGFSYGDV   1150
LGAGAGWAKS VLYHEGVRSQ FSKFFNERQD TFAFGACNGC QFLSRLKDII   1200
PGCENWPSFE RNVSEQYEAR VCMVQISQEK DNSSEESVFL NGMAGSKLPI   1250
AVAHGEGKAT FSKSAEQLEK FEKDGLCCIR YVDNYGNVTE RFPFNPNGST   1300
NGIAGIKSPN GRVLAMMPHP ERVCRLEANS WYPEGKYEEW GGYGPWIRLF   1350
RSARRWVG                                                 1358