SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameADE13
Systematic nameYLR359W
DescriptionAdenylosuccinate lyase

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1K196        
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"A proteomics approach to understanding protein ubiquitination."
Peng J, Schwartz D, Elias JE, Thoreen CC, Cheng D, Marsischky G, Roelofs J, Finley D, Gygi SP.
Nat Biotechnol. 21(8):921-6 (2003) [12872131]

Cross References
Swiss-Prot accessionQ05911
SGD YLR359W
Gene Ontology (GO)
Molecular functionGO:0004018adenylosuccinate lyase activityIMP:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0006189'de novo' IMP biosynthetic processIMP:SGD.
EC number 4.3.2.2

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length482
Molecular weight54510

	---------+----------+----------+----------+----------+
MPDYDNYTTP LSSRYASKEM SATFSLRNRF STWRKLWLNL AIAEKELGLT   50
VVTDEAIEQM RKHVEITDDE IAKASAQEAI VRHDVMAHVH TFGETCPAAA   100
GIIHLGATSC FVTDNADLIF IRDAYDIIIP KLVNVINRLA KFAMEYKDLP   150
VLGWTHFQPA QLTTLGKRAT LWIQELLWDL RNFERARNDI GLRGVKGTTG   200
TQASFLALFH GNHDKVEALD ERVTELLGFD KVYPVTGQTY SRKIDIDVLA   250
PLSSFAATAH KMATDIRLLA NLKEVEEPFE KSQIGSSAMA YKRNPMRCER   300
VCSLARHLGS LFSDAVQTAS VQWFERTLDD SAIRRISLPS AFLTADILLS   350
TLLNISSGLV VYPKVIERRI KGELPFMATE NIIMAMVEKN ASRQEVHERI   400
RVLSHQAAAV VKEEGGENDL IERVKRDEFF KPIWEELDSL LEPSTFVGRA   450
PQQVEKFVQK DVNNALQPFQ KYLNDEQVKL NV                      482

	* Ubiquitinated lysine is denoted as red color.